What denotes Rheumatoid Arthritis?

Rheumatoid arthritis is characterized as an autoimmune inflammatory disease, which means that the body's immune system mistakenly attacks its own tissues, particularly the synovium, which lines the joints. This results in inflammation, causing symptoms such as pain, swelling, stiffness, and potential joint damage over time. Unlike degenerative joint diseases, which are typically associated with wear and tear of cartilage, rheumatoid arthritis involves a systemic immune response that leads to joint inflammation and can affect other systems in the body as well.

The autoimmune aspect is crucial in understanding the underlying processes of rheumatoid arthritis. It distinguishes this condition from other types of joint issues, such as those caused by infections or degeneration. While the option referring to a microbial infection indicates an acquired condition, rheumatoid arthritis arises from a malfunctioning immune response rather than an infection or cancer, which also helps clarify why the other choices do not apply.