Which of the following is NOT associated with chronic inflammation?

Chronic inflammation is characterized by a prolonged inflammatory response that can damage tissues and contribute to various diseases. In the context of the diseases listed, arthritis, diabetes, and Alzheimer disease have well-documented associations with chronic inflammation.

Arthritis involves the immune system attacking joint tissues, leading to persistent inflammation and pain. Similarly, diabetes, particularly type 2 diabetes, is linked to chronic low-grade inflammation that affects insulin resistance and metabolic processes. Alzheimer disease is associated with neuroinflammation, which contributes to neuronal damage and cognitive decline over time.

Asthma, while it does involve inflammation, is typically categorized as an acute inflammatory condition where the inflammation is often a response to specific triggers such as allergens or irritants, leading to bronchoconstriction and respiratory symptoms. The inflammatory response in asthma can be variable and often episodic, differentiating it from the ongoing inflammation characteristic of the other conditions mentioned.

Thus, the correct answer is based on the distinction that asthma, while it can involve inflammation, does not express the chronic nature that is associated with arthritis, diabetes, or Alzheimer disease.